Vaccines and Pregnancy

Updated September 25, 2023


Below is a table summarizing the recommended use of vaccines during pregnancy in the U.S. Included in this table is information most relevant to women of child-bearing age for certain vaccines. For more information about these vaccines and their use outside of pregnancy, please see the individual summaries on the following pages, or the websites listed below.

The American College of Obstetricians and Gynecologists (ACOG) provides information on vaccinating during pregnancy at the following website: providers/pregnancy/pregnancy.php. The Centers for Disease Control and Prevention (CDC) lists guidelines for vaccinating during pregnancy at the following website:

Vaccines and Pregnancy
VaccineIndication During PregnancyRelevant Information
Hepatitis ANot routinely recommended during pregnancyThe low theoretical risk of vaccination should be weighed against the risk of hepatitis A infection among pregnant individuals at high risk of exposure.
Hepatitis BNot routinely recommended during pregnancyIn order to prevent perinatal hepatitis B infection, all pregnant individuals should be routinely screened for hepatitis B surface antigen (HBsAg), and subsequent postexposure immunoprophylaxis should be administered to infants born to women who are HBsAg-positive or of unknown HBsAg status.
Herpes ZosterContraindicated during pregnancy 
Human Papillomavirus (HPV)Not routinely recommended during pregnancyIf a woman is discovered to be pregnant after receiving HPV vaccine, no intervention is indicated. The remaining doses in the series should be delayed until after the pregnancy.
Inactivated Influenza Vaccine (IIV)Routinely recommended during pregnancyPregnant individuals and young children are at increased risk of complications and hospitalizations from influenza.
Live Attenuated Influenza Vaccine (LAIV)Contraindicated during pregnancy 
Measles, Mumps and Rubella (MMR)Contraindicated during pregnancyVaccination against rubella is emphasized for all non-pregnant individuals of childbearing age, especially those born outside of the U.S. Those without evidence of immunity should be given MMR vaccine, excluding women who are pregnant or currently attempting to become pregnant. Pregnancy should be avoided for at least 4 weeks following MMR vaccination; however, inadvertent MMR vaccination should not be considered an indication for termination of the pregnancy.
MeningococcalNot routinely recommended during pregnancyPregnancy should not preclude indicated MenACWY vaccination. MenB vaccination should be deferred in pregnant and lactating women unless they are at increased risk and the benefits of vaccination outweigh the potential risks.
PneumococcalNot routinely recommended during pregnancyIndividuals who are at high risk of pneumococcal disease should be vaccinated before pregnancy, if possible.
Inactivated Polio Vaccine (IPV)Not routinely recommended during pregnancyVaccination of pregnant individuals with IPV should generally be avoided. However, if a pregnant individual is at increased risk for polio infection and requires immediate protection, IPV can be administered in accordance with the recommended schedule.
Tetanus, Diphtheria and Pertussis (Tdap)Routinely recommended during pregnancyMost deaths from pertussis occur in the first few months of life prior to receipt of routine infant vaccines against pertussis. Vaccination with Tdap during pregnancy helps protect infants from pertussis.
VaricellaContraindicated during pregnancyPregnancy should be avoided for at least 4 weeks following varicella vaccination; however, inadvertent varicella vaccination should not be considered an indication for termination of the pregnancy.