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Components of
Typhoid Vaccines

Excipients Table
Allergens Table
Components Table
 

Indication

Induction of active immunity against typhoid fever

Proprietary Name

Typhim Vi

Vivotif Berna

Manufacturers

sanofi pasteur

Berna

Viability

Inactivated

Live, attenuated

Microorganism

Salmonella enterica serovar typhi, S typhi Ty2 strain

Salmonella typhi Ty21a

Dose:

0.5 mL

 One enteric-coated capsule

Route

Intramuscular

Oral

Dose form

Liquid solution

Capsule

Appearance

Clear, colorless

Salmon/white capsule

Concentration

Purified Vi polysaccharide, 25 mcg

Salmonella typhi Ty21a, 2-6x109 colony-forming units

Preservatives

Phenol, 0.25%

None

Adjuvant

None

None

Excipients

Sodium chloride, 8.3 mg/mL

Disodium phosphate, 0.13 mg/mL

Monosodium phosphate, 0.046 mg/mL

Polydimethylsilozane-based antifoam agents, residual

Sucrose, 26130 mg

Ascorbic acid, 15 mg

Amino acid mixture, 1.47 mg

Magnesium stearate 3.64.4 mg

Allergens

None

Lactose, 100180 mg

Yeast extract from media

Media

Semi-synthetic medium without animal proteins

Yeast extract (consisting of casein, dextrose and galactose)

Packaging

Single-dose syringe without needle

20-dose vial

Single foil blister contains 4 doses of vaccine

Routine Storage

2 to 8 C (36 to 46 F)

Do not freeze

2 to 8 C (36 to 46 F)

Do not freeze

updated August 2005

 

This page was last updated on February 12, 2014

2014 Institute for Vaccine Safety