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Components of
Rabies Vaccines

Excipients Table
Allergens Table
Components Table

 

Indication

Induction of active immunity against rabies virus, either before or after viral exposure

Proprietary Name

Imovax Rabies

RabAvert

Manufacturers

sanofi pasteur

Novartis

Viability

Inactivated

Inactivated

Microorganism

Virus, genus Lyssavirus, family Rhabdoviridae

Virus, genus Lyssavirus, family Rhabdoviridae

Dose

1.0 mL

1.0 mL

Route

Intramuscular

Intramuscular

Dose form

Powder

Powder

Appearance

Creamy white to orange - After reconsitution, pink - red

White, freeze-dried - After reconstitution, clear to slightly opaque, colorless suspension

Concentration (per 1.0 mL)

Rabies antigen, 2.5 IU

Rabies antigen, 2.5 IU

Preservatives

None

None

Adjuvant

None

None

Excipients

Phenol red indicator, 20 mg

Potassium glutamate, 1 mg

Polygeline, 12 mg

Human Serum Albumin, <0.3 mg

Sodium EDTA, 0.3 mg

Allergens

Albumin, <100 mg

Neomycin sulfate, < 150 mcg

Neomycin, < 1 mcg

Bovine gelatin (polygeline), < 12 mg

Ovalbumin, < 3 ng

Bovine serum used in cell culture process

Chicken protein, trace amounts

Chlortetracycline, < 20 ng

Amphotericin B, < 2 ng

Media

Human diploid cells, MRC5 strain

Synthetic cell culture medium with the addition of human albumin, polygeline, antibiotics

Packaging

Single dose vial with diluent and syringe/needle

Single dose vial with diluent and syringe/needles

Routine Storage

2 to 8 C (36-46 F)

Do not freeze

2 to 8 C (36-46 F)

Use immediately after reconstitution

updated August 2005

 

This page was last updated on February 12, 2014

2014 Institute for Vaccine Safety