Components of

Pneumococcal Vaccines

Components Page
Excipients Table
Allergens Table
     
Name Prevnar-13 Pneumovax 23
Manufacturer Wyeth Pharmaceuticals Merck
Viability Inactivated Inactivated
Indicated Ages 6 weeks and older 2 years and older
Dose 0.5 mL 0.5 mL
Schedule Ages 6 wks-5 yrs: 4 doses
Ages 6 yrs+: 1 dose
1 dose
Route Intramuscular Intramuscular or subcutaneous
Appearance Homogenous and white Clear and colorless
Concentration Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 7F, 9V, 14, 18C, 19A, 19F, 23F saccharides: 2.2 mcg each
Serotype 6B saccharides: 4.4 mcg
Streptococcus pneumoniae serotypes 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, 33F saccharides: 25 mcg each
Preservative None Phenol, 0.25%
Adjuvant Aluminum Phosphate Aluminum
Excipients CRM197 carrier protein, 34 mcg
Aluminum phosphate, 125 mcg aluminum
• Polysorbate 80, 100 mcg
Unspecified amounts:
• Cell culture media
• Fetal bovine serum, trace amounts
• PCV 1&2
• Casamino Acids
 
Allergens
Media Yeast extract-based Medium
Packaging • Prefilled syringe, single
• Prefilled syringe, 10-pack
• 5-dose vial
• Single-dose vial, 10-pack
• Single-dose pre-filled syringe, 10-pack
• Single-dose pre-filled syringe
Storage 2-8C (36-46F)
Do not freeze.
2-8C (35-46F)
Do not freeze
PI date August 2017 May 2015
    table last updated 3/8/18