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Components of
Pneumococcal Vaccine

Excipients Table
Allergens Table
Components Table

 

Indication

Immunity in infants and children against S. pneumoniae

Proprietary Name

Prevnar

Pneumovax 23

Manufacturers

Wyeth-Lederle

Merck

Viability

Inactivated

Inactivated

Microorganism

Streptococcus pneumoniae 7-valent serotype

Streptococcus pneumoniae
23-valent serotype
 

Dose

0.5 mL

0.5 mL

Route

Intramuscular

Intramuscular or Subcutaneous

Dose form

Suspension

Solution

Appearance

Homogeneous, white suspension

Clear, colorless solution

Concentration (per 0.5 mL)

Serotypes 4, 9V, 14, 18C, 19F, and 23F, 2 mcg each

Serotypes 6B, 4 mcg

23 polysaccharides, 25 mcg for each (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, 33F)

Preservatives

None

 Phenol, 0.25%

Adjuvants

Diphtheria CRM197, 20 mcg
Aluminum phosphate, 0.125 mg
None

Excipients

None None

Allergens

Dry natural rubber None

Media

Soy peptone broth Bovine proteins and other macromolecular components

Packaging

Vial, 1 dose (5 per package) Vials, 5-dose, 10 5-dose vials, 10 single-dose vial

Routine storage

2 to 8° C (35-46° F)

Do not freeze

2 to 8° C (35-46° F)

Do not freeze

updated July 2005

This page was last updated on January 23, 2008

© 2004 Institute for Vaccine Safety