Issues: Vax Specific
● Anthrax
● Hepatitis B
● Hib
● Influenza
● Lyme Disease ● Meningococcal
● MMR
● Polio
● Rotavirus
● Smallpox
● Tdap/Td
● Varicella
● Yellow Fever
Issues: Misc
● Exemptions
● Legislation
● New Vax Status
● Thimerosal
● Independent Vax Safety Board
Vaccine Info
● 2008 Schedule
● ACIP Recs
● Components ● IOM Reports
● Vax Injury Comp Program ● Manufacturer Links
● Package Inserts
● Reporting AEs
● Thimerosal Table
● VAERS
● VISs
Links
Search
About IVS
● Faculty Biographies
● Publications
● Donations
Email IVS
Disclaimers & Privacy
Institute for Vaccine Safety
Johns Hopkins Bloomberg School of Public Health
615 N. Wolfe Street
Room W5041
Baltimore, MD 21205
www.vaccinesafety.edu
Components of Pneumococcal Vaccine Excipients Table Allergens Table Components Table Indication Immunity in infants and children against S. pneumoniae Proprietary Name Prevnar Pneumovax 23 Manufacturers Wyeth-Lederle Merck Viability Inactivated Inactivated Microorganism Streptococcus pneumoniae 7-valent serotype Streptococcus pneumoniae 23-valent serotype Dose 0.5 mL 0.5 mL Route Intramuscular Intramuscular or Subcutaneous Dose form Suspension Solution Appearance Homogeneous, white suspension Clear, colorless solution Concentration (per 0.5 mL) Serotypes 4, 9V, 14, 18C, 19F, and 23F, 2 mcg each Serotypes 6B, 4 mcg 23 polysaccharides, 25 mcg for each (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, 33F) Preservatives None Phenol, 0.25% Adjuvants Diphtheria CRM197, 20 mcg Aluminum phosphate, 0.125 mg None Excipients None None Allergens Dry natural rubber None Media Soy peptone broth Bovine proteins and other macromolecular components Packaging Vial, 1 dose (5 per package) Vials, 5-dose, 10 5-dose vials, 10 single-dose vial Routine storage 2 to 8° C (35-46° F) Do not freeze 2 to 8° C (35-46° F) Do not freeze updated July 2005 This page was last updated on January 23, 2008 © 2004 Institute for Vaccine Safety
Components of Pneumococcal Vaccine
Excipients Table Allergens Table Components Table
Indication
Immunity in infants and children against S. pneumoniae
Proprietary Name
Prevnar
Pneumovax 23
Manufacturers
Wyeth-Lederle
Merck
Viability
Inactivated
Microorganism
Streptococcus pneumoniae 7-valent serotype
Dose
0.5 mL
Route
Intramuscular
Intramuscular or Subcutaneous
Dose form
Suspension
Solution
Appearance
Homogeneous, white suspension
Clear, colorless solution
Concentration (per 0.5 mL)
Serotypes 4, 9V, 14, 18C, 19F, and 23F, 2 mcg each
Serotypes 6B, 4 mcg
23 polysaccharides, 25 mcg for each (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, 33F)
Preservatives
None
Phenol, 0.25%
Adjuvants
Excipients
Allergens
Media
Packaging
Routine storage
2 to 8° C (35-46° F)
Do not freeze
updated July 2005
This page was last updated on January 23, 2008
© 2004 Institute for Vaccine Safety