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MMR    

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● Smallpox

Tdap/Td

Varicella

Yellow Fever

 

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Vaccine Excipients

Allergens Table
Components Table

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Excipient

Type

Vaccine Name

Vaccine Type

Amount per dose

2-Phenoxyethanol

Stabilizer

Adacel

Tdap

3.3 mg (0.6% v/v) (not as a preservative)

2-Phenoxyethanol

Stabilizer

Daptacel

DTaP

3.3 mg (0.6% v/v) (not as a preservative)

2-Phenoxyethanol

Preservative

IPOL

Polio

0.5% (as a preservative)

2-Phenoxyethanol

Stabilizer

Pentacel

DTaP+IPV+Hib

3.3 mg (0.6 v/v) (not as a preservative)

2-Phenoxyethanol

Stabilizer

Quadracel

DTaP+IPV

3.3 mg (0.6 v/v) (not as a preservative)

3-O-desacyl-4’-monophosphoryl lipid A (MPL)

Adjuvant

Cervarix

HPV

50 mcg

Albumin, Bovine

Stabilizer

Ixiaro

Japanese Encephalitis

≤ 100 ng/mL

Albumin, Bovine

Stabilizer

Quadracel

DTaP+IPV

≤ 50 ng

Albumin, Bovine

Stabilizer

Vaqta

HepA

< 0.1 ng

Albumin, Calf Serum

Stabilizer

Kinrix

DTaP+IPV

VERO cell culture growth

Albumin, Calf Serum

Stabilizer

Zostavax

Zoster

Trace amounts

Albumin, Calf Serum Protein

Stabilizer

IPOL

IPV

< 1 ppm50 ng

Albumin, Calf Serum Protein

Stabilizer

Pediarix

DTaP+HepB+IPV

VERO cell culture growth≤ 50 ng residual

Albumin, Calf Serum Protein

Stabilizer

Pentacel

DTaP+IPV+Hib

≤ 50 ng residual

Albumin, Egg (Ovalbumin)

Residual Medium

Afluria

Influenza

≤ 1 mcg

Albumin, Egg (Ovalbumin)

Residual Medium

Fluarix Quad

Influenza

≤ 0.05 mcg

Albumin, Egg (Ovalbumin)

Residual Medium

Flulaval Quad

Influenza

≤ 0.3 mcg

Albumin, Egg (Ovalbumin)

Residual Medium

FluMist Quad

Influenza

≤ 0.24 mcg

Albumin, Egg (Ovalbumin)

Residual Medium

Fluvirin

Influenza

≤ 1 mcg

Albumin, Egg (Ovalbumin)

Residual Medium

FluZone

Influenza

Limited quantity

Albumin, Egg (Ovalbumin)

Residual Medium

RabAvert

Rabies

< 3 ng/dose

Albumin, Fetal Bovine Serum

Stabilizer

MMR-II

MMR

< 1 ppm

Albumin, Fetal Bovine Serum

Stabilizer

RotaTeq

Rotavirus

Trace amounts

Albumin, Fetal Bovine Serum

Stabilizer

Varivax

Varicella

Trace amounts

Albumin, Human

Stabilizer

Imovax

Rabies

< 100 mg

Albumin, Human Serum

Diluent/Stabilizer

MMR-II

MMR

≤ 0.3 mg

Albumin, Human Serum

Diluent/Stabilizer

ProQuad

MMRV

0.31 mg

Albumin, Human Serum

Diluent/Stabilizer

RabAvert

Rabies

< 0.3 mg

Aluminum

Adjuvant

Adacel

Tdap

0.33 mg 

Aluminum

Adjuvant

Bexsero

Meningococcal Group B

1.5 mg aluminum hydroxide

Aluminum

Adjuvant

BioThrax

Anthrax

1.2 mg/mL

Aluminum

Adjuvant

Boostrix

Tdap

≤ 0.39 mg

Aluminum

Adjuvant

Cervarix

HPV

0.5 mg aluminum hydroxide

Aluminum

Adjuvant

Comvax

Hib+HepB

225 mcg

Aluminum

Adjuvant

Daptacel

DTaP

0.33 mg

Aluminum

Adjuvant

DT

DT

≤ 0.17 mg

Aluminum

Adjuvant

Engerix-B

HepB

0.5 mg/mL as aluminum hydroxide

Aluminum

Adjuvant

Gardasil

HPV 9-valent

225 mcg

Aluminum

Adjuvant

Gardasil 9

HPV

500 mcg

Aluminum

Adjuvant

Infanrix

DTaP

≤ 0.625 mg

Aluminum

Adjuvant

Ixiaro

Japanese Encephalitis

250 mcg aluminum hydroxide

Aluminum

Adjuvant

Kinrix

DTaP+IPV

≤ 0.6 mg

Aluminum

Adjuvant

Pediarix

DTaP+HepB+IPV

≤ 0.85 mg

Aluminum

Adjuvant

PedvaxHIB

Hib+HepB

225 mcg

Aluminum

Adjuvant

Pentacel

DTaP+IPV+Hib

0.33 mg

Aluminum

Adjuvant

Prevnar

Pneumococcal 7-valent

0.125 mg

Aluminum

Adjuvant

Prevnar 13

Pneumococcal 13-valent

0.125 mg

Aluminum

Adjuvant

Quadracel

DTaP+IPV

0.33 mg

Aluminum

Adjuvant

Recombivax HB

HepB

0.5 mg/mL

Aluminum

Adjuvant

Td

Td

≤ 0.53 mg

Aluminum

Adjuvant

Tenivac

Td

0.33 mg

Aluminum

Adjuvant

Tetanus & Diphtheria Toxoids

TT

≤ 0.25

Aluminum

Adjuvant

Twinrix

HepA+HepB

0.45 mg

Aluminum

Adjuvant

Vaqta

HepA

0.45 mg

Aluminum

Adjuvant

Trumenba

Meningococcal Group B

0.25 mg

Amino Acid

Medium Nutrient

BioThrax

Anthrax

Unspecified amount in growth medium

Amino Acid

Medium Nutrient

Cervarix

HPV

Unspecified amount in growth medium

Amino Acid

Medium Nutrient

Comvax

Hib+HepB

Unspecified amount in growth medium

Amino Acid

Medium Nutrient

Flublok

Influenza

Ingredient in growth medium

Amino Acid

Medium Nutrient

Gardasil

HPV

Ingredient in growth medium

Amino Acid

Medium Nutrient

Menveo

Meningococcal

In growth medium

Amino Acid

Medium Nutrient

MMR-II

MMR

In growth medium

Amino Acid

Medium Nutrient

PedvaxHIB

Hib+HepB

Amount not specified in Package Insert

Amino Acid

Medium Nutrient

Recombivax HB

HepB

In fermentation medium

Amino Acid

Medium Nutrient

Rotarix

Rotavirus

In DMEM (Dulbecco's Modified Eagle Medium)

Amino Acid

Medium Nutrient

Twinrix

HepA+HepB

Amount not specified in Package Insert

Amino Acid

Medium Nutrient

Vivotif

Typhoid

1.4-7 mg/capsule

Ammonium Sulfate

Protein Purifier

ActHIB

Hib

Ingredient in purification

Ammonium Sulfate

Protein Purifier

Adacel

Tdap

Ingredient in purification

Ammonium Sulfate

Protein Purifier

Daptacel

DTaP

Ingredient in purification

Ammonium Sulfate

Protein Purifier

DT

DT

Ingredient in purification

Ammonium Sulfate

Protein Purifier

Menactra

Meningococcal

Ingredient in purification

Ammonium Sulfate

Protein Purifier

Pentacel

DTaP+IPV+Hib

Ingredient in purification

Ammonium Sulfate

Protein Purifier

Prevnar

Pneumococcal 7-valent

Ingredient in purification

Ammonium Sulfate

Protein Purifier

Prevnar 13

Pneumococcal 13-valent

Ingredient in purification

Ammonium Sulfate

Protein Purifier

Td

Td

Ingredient in purification

Ammonium Sulfate

Protein Purifier

Tenivac

Td

Ingredient in purification

Amphotericin B

Antimicrobial

RabAvert

Rabies

< 2 ng

Ascorbic Acid

Anitoxidant

Vivotif

Typhoid

1-5 mg/capsule

Barium

 

Fluad

Influenza

<0.5 mcg

Benzethonium Chloride

Preservative

BioThrax

Anthrax

25 mcg/mL

Beta-Propiolactone

Viral Inactivator

Afluria

Influenza

< 2 ng

Beta-Propiolactone

Viral Inactivator

Flucelvax Quad

Influenza

≤ 0.5 mcg

Beta-Propiolactone

Viral Inactivator

Fluvirin

Influenza

≤ 0.5 mcg

Beta-Propiolactone

Viral Inactivator

Imovax

Rabies

< 50 ppm

Bovine Casein

Medium Nutrient

Boostrix

Tdap

Amount not specified in Package Insert

Bovine Casein

Medium Nutrient

Infanrix

DTaP

12.2-18.3 ng/mL

Bovine Casein

Medium Nutrient

Kinrix

DTaP+IPV

Ingredient in Latham medium

Bovine Casein

Medium Nutrient

Pediarix

DTaP+HepB+IPV

Ingredient of Latham medium

Bovine Casein

Medium Nutrient

Vivotif

Typhoid

Ingredient in medium

Bovine Extract

Medium Nutrient

Boostrix

Tdap

Amount not specified in Package Insert

Bovine Extract

Medium Nutrient

DT

DT

Amount not specified in Package Insert

Bovine Extract

Stabilizer

Infanrix

DTaP

Ingredient in Fenton medium

Bovine Extract

Stabilizer

Kinrix

DTaP+IPV

Ingredient in Fenton medium

Bovine Extract

Stabilizer

Pediarix

DTaP+HepB+IPV

Ingredient of Fenton medium

Bovine Extract

Stabilizer

Td

Td

Ingredient in Mueller's media

Bovine, Casamino Acid

Stabilizer

Adacel

Tdap

Ingredient in growth medium

Bovine, Casamino Acid

Stabilizer

Daptacel

DTaP

Ingredient in growth medium

Bovine, Casamino Acid

Stabilizer

Menomune

Meningococcal

Ingredient in growth medium

Bovine, Casamino Acid

Stabilizer

Pentacel

DTaP+IPV+Hib

Ingredient in growth medium

Bovine, Casamino Acid

Stabilizer

Prevnar

Pneumococcal 7-valent

Ingredient in growth medium

Bovine, Casamino Acid

Stabilizer

Prevnar 13

Pneumococcal 13-valent

Ingredient in growth medium

Bovine, Casamino Acid

Stabilizer

Tenivac

Td

Ingredient in growth medium

Calcium Carbonate

Buffer

Rotarix

Rotavirus

Ingredient in diluent

Calcium Chloride

Medium Nutrient

Afluria

Influenza

1.5 mcg

Calcium Chloride

Medium Nutrient

Rotarix

Rotavirus

In DMEM (Dulbecco’s Modified Eagle Medium)

Carbohydrates

Medium Nutrient

Gardasil

HPV

Ingredient in fermentation medium

Chick Embryo

Residual Medium

MMR-II

MMR

No intact cells (may have trace residual protein)

Chick Embryo

Residual Medium

ProQuad

MMRV

No intact cells (may have trace residual protein)

Chick Embryo

Residual Medium

YF-Vax

Yellow Fever

Not listed as an ingredient; Yellow Fever virus is grown in chicken embryos

Chick fibroblasts

Protein Purifier

RabAvert

Rabies

Growth medium

Chlortetracycline

Antimicrobial

RabAvert

Rabies

1 mcg

Citric Acid Monohydrate

 

Fluad

Influenza

0.04 mg

CTAB

Protein Purifier

Fluad

Influenza

≤12 mcg

CTAB

Protein Purifier

Flucelvax Quad

Influenza

≤ 13.5 mcg

Dextrose

Medium Nutrient

Comvax

Hib+HepB

Amount not specified in Package Insert

Dextrose

Medium Nutrient

Recombivax HB

HepB

Ingredient of fermentation medium

Dextrose

Medium Nutrient

Vivotif

Typhoid

Ingredient in medium

D-glucose

Medium Nutrient

Rotarix

Rotavirus

In DMEM (Dulbecco’s Modified Eagle Medium)

Dimethyl-beta-cyclodextrin

Medium Nutrient

Adacel

Tdap

Amount not specified in Package Insert

Dimethyl-beta-cyclodextrin

Medium Nutrient

Daptacel

DTaP

Amount not specified in Package Insert

Dimethyl-beta-cyclodextrin

Medium Nutrient

Pentacel

DTaP+IPV+Hib

Ingredient of Stainer-Scholte medium

DNA

Residual Medium

Flublok

Influenza

≤ 10 ng

DNA

Residual Medium

Flucelvax Quad

Influenza

≤ 10 ng MDCK cell

DNA

Residual Medium

Ixiaro

Japanese Encephalitis

≤ 200 pg/mL ('host cell DNA')

DNA

Residual Medium

ProQuad

MMRV

Residual component of MRC-5 cells

DNA

Residual Medium

RotaTeq

Rotavirus

DNA

Residual Medium

Vaqta

HepA

< 4 x 10–6 mcg

DNA

Residual Medium

Varivax

Varicella

Residual component of MRC-5 cells

DNA

Residual Medium

Zostavax

Zoster

Residual component of MRC-5 cells

EDTA

Preservative

FluMist Quad

Influenza

<0.37 mcg

EDTA

Preservative

RabAvert

Rabies

0.3 mg sodium EDTA

EDTA

Preservative

Varivax

Varicella

Trace amounts

Egg Protein

Residual Medium

Fluad

Influenza

<0.4 mcg

Egg Protein

Residual Medium

Fluvirin

Influenza

≤ 1 mcg ovalbumin

Ferric (III) Nitrate

Medium Nutrient

Rotarix

Rotavirus

In DMEM (Dulbecco’s Modified Eagle Medium)

Formaldehyde

Inactivating Agent

ActHIB

Hib

< 0.5 mcg

Formaldehyde

Inactivating Agent

Adacel

Tdap

≤ 5 mcg

Formaldehyde

Preservative

BioThrax

Anthrax

100 mg/mL

Formaldehyde

Inactivating Agent

Boostrix

Tdap

≤ 100 mcg (residual)

Formaldehyde

Inactivating Agent

Comvax

Hib+HepB

≤ 0.0004% (w/v) residual

Formaldehyde

Inactivating Agent

Daptacel

DTaP

≤ 5 mcg (residual)

Formaldehyde

Inactivating Agent

DT

DT

< 0.02%

Formaldehyde

Inactivating Agent

Fluad

Influenza

≤10 mcg

Formaldehyde

Inactivating Agent

Fluarix Quad

Influenza

≤ 5 mcg

Formaldehyde

Inactivating Agent

Flulaval Quad

Influenza

≤ 25 mcg

Formaldehyde

Inactivating Agent

FluZone

Influenza

≤ 100 mcg/.5mL

Formaldehyde

Inactivating Agent

FluZone High-Dose

Influenza

≤ 100 mcg

Formaldehyde

Inactivating Agent

FluZone Intradermal Quad

Influenza

≤ 20 mcg

Formaldehyde

Inactivating Agent

FluZone Quad

Influenza

≤ 100 mcg/0.5mL in Fluzone Intradermal

Formaldehyde

Inactivating Agent

Hiberix

Hib

< 0.5 mcg (residual)

Formaldehyde

Inactivating Agent

Infanrix

DTaP

≤ 100 mcg (residual)

Formaldehyde

Inactivating Agent

IPOL

Polio

≤ 0.02%

Formaldehyde

Inactivating Agent

Ixiaro

Japanese Encephalitis

≤ 200 pmm

Formaldehyde

Inactivating Agent

JE-Vax

Japanese Encephalitis

< 100 mcg

Formaldehyde

Inactivating Agent

Kinrix

DTaP+IPV

≤ 100 mcg (residual)

Formaldehyde

Inactivating Agent

Menactra

Meningococcal

< 2.66 mcg

Formaldehyde

Inactivating Agent

Menhibrix

Meningococcal CY+Hib

≤ 0.72 mcg

Formaldehyde

Inactivating Agent

Menveo

Meningococcal

≤ 0.3 mcg

Formaldehyde

Inactivating Agent

Pediarix

DTaP+HepB+IPV

≤ 100 mcg (residual)

Formaldehyde

Inactivating Agent

Pentacel

DTaP+IPV+Hib

≤ 5 mcg (residual)

Formaldehyde

Inactivating  Agent

Quadracel

DTaP+IPV

≤ 5 mcg

Formaldehyde

Inactivating Agent

Recombivax HB

HepB

< 15 mcg/mL (residual)

Formaldehyde

Inactivating Agent

Td

Td

100 mcg

Formaldehyde

Inactivating Agent

Tenivac

Td

≤ 5 mcg (residual)

Formaldehyde

Inactivating Agent

Tetanus and Diphtheria Toxoids

Td

≤ 0.02% (residual)

Formaldehyde

Inactivating Agent

Twinrix

HepA+HepB

≤ 0.1 mg formalin

Formaldehyde

Inactivating Agent

Vaqta

HepA

< 0.8 mcg

Galactose

Medium Nutrient

Vivotif

Typhoid

Ingredient in medium

Gelatin

Stabilizer

FluZone

Influenza

0.05% in 0.25 mL and 0.5 mL

Gelatin

Manufacturing residue

JE-Vax

Japanese Encephalitis

500 mcg/1 mL dose

Gelatin

Gelatin Capsules

Vivotif

Typhoid

Gelatin capsules

Gelatin

Stabilizer

YF-Vax

Yellow Fever

Amount not specified in Package Insert

Gelatin, Bovine

Stabilizer, solvent

RabAvert

Rabies

< 12 mg polygeline

Gelatin, hydrolyzed

Stabilizer

MMR-II

MMR

14.5 mg

Gelatin, hydrolyzed

Stabilizer

ProQuad

MMRV

11 mg

Gelatin, hydrolyzed

Stabilizer

Varivax

Varicella

12.5 mg

Gelatin, Porcine, Hydrolyzed

Stabilizer

FluMist Quad

Influenza

2.00 mg/0.2 mLdose

Gelatin, Porcine, Hydrolyzed

Stabilizer

Zostavax

Varicella Zoster

15.58 mg

Gentamicin Sulfate

Antimicrobial

Fluarix Quad

Influenza

≤ 0.15 mcg

Gentamicin Sulfate

Antimicrobial

FluMist Quad

Influenza

< 0.015 mcg/mL

Glutamate

Medium Nutrient

MMR-II

MMR

Ingredient in growth medium (Medium 199)

Glutaraldehyde

Inactivating Agent

Adacel

Tdap

< 50 ng (residual)

Glutaraldehyde

Inactivating Agent

Boostrix

Tdap

Amount not specified in Package Insert

Glutaraldehyde

Inactivating Agent

Daptacel

DTaP

< 50 ng (residual)

Glutaraldehyde

Inactivating Agent

Infanrix

DTaP

Amount not specified in Package Insert

Glutaraldehyde

Inactivating Agent

Kinrix

DTaP+IPV

Amount not specified in Package Insert

Glutaraldehyde

Inactivating Agent

Pediarix

DTaP+HepB+IPV

Amount not specified in Package Insert

Glutaraldehyde

Inactivating Agent

Pentacel

DTaP+IPV+Hib

< 50 ng (residual)

Glutaraldehyde

Inactivating Agent

Quadracel

DTaP+IPV

< 50 ng

Hexadecyltrimethylammonium Bromide

Protein Purifier

Typhim Vi

Typhoid

Amount not specified in Package Insert

Histidine

Medium Nutrient

Bexsero

Meningococcal Group B

0.776 mg

Histidine

Medium Nutrient

Trumenba

Meningococcal Group B

10 mM

Hydrocortisone

Medium Nutrient

Fluarix Quad

Influenza

≤ 0.0016 mcg

Insect cell

Residual medium

Cervarix

HPV

40 ng (residual)

Kanamycin

 

Fluad

Influenza

≤ 0.03 mcg

Lactalbumin Hydrolysate

Medium Nutrient

Kinrix

DTaP+IPV

Ingredient in growth medium

Lactalbumin Hydrolysate

Medium Nutrient

Pediarix

DTaP+HepB+IPV

Ingredient in growth medium

Lactose

Stabilizer

Hiberix

Hib

12.6 mg

Lactose

Stabilizer

Menomune

Meningococcal

2.5-5 mg

Lactose

Stabilizer

Vivotif

Typhoid

100-180 mg/capsule

L-cystine

Medium Nutrient

Rotarix

Rotavirus

Amount not specified in Package Insert

L-histidine

Medium Nutrient

Gardasil

HPV

0.78 mg

L-histidine

Medium Nutrient

Gardasil 9

HPV

0.78 mg

L-tyrosine

Medium Nutrient

Rotarix

Rotavirus

Amount not specified in Package Insert

Magnesium Stearate

Lubricant for capsule filling

Vivotif

Typhoid

3.6-4.4 mg/capsule

Magnesium Sulfate

Medium Nutrient

Rotarix

Rotavirus

Amount not specified in Package Insert

Monosodium glutamate

Stabilizer

FluMist Quad

Influenza

0.188 mg/0.2 mL dose

Monosodium L-glutamate

Stabilizer

ProQuad

MMRV

0.40 mg

Monosodium L-glutamate

Stabilizer

Varivax

Varicella

0.5 mg

Monosodium L-glutamate

Stabilizer

Zostavax

Varicella Zoster

0.62 mg

Mouse Serum Protein

Manufacturing residue

JE-Vax

Japanese Encephalitis

< 50 ng

MRC-5

Manf residue

Imovax

Rabies

Amount not specified in Package Insert

MRC-5

Growth Medium

Pentacel

DTaP+IPV+Hib

Amount not specified in Package Insert

MRC-5

Manf residue

ProQuad

MMRV

Residual

MRC-5

Manf residue

Twinrix

HepA+HepB

≤2.5 mcg

MRC-5

Manf residue

Vaqta

HepA

Amount not specified in Package Insert

MRC-5

Manf residue

Varivax

Varicella

Residual components

MRC-5

Manf residue

Zostavax

Varicella Zoster

Residual

Neomycin

Antimicrobial

Fluad

Influenza

≤ 0.02 mcg

Neomycin

Antimicrobial

Fluvirin

Influenza

≤2.5 mcg

Neomycin

Antimicrobial

IPOL

IPV

< 5 ng

Neomycin

Antimicrobial

Kinrix

DTaP+IPV

≤ 0.05 ng

Neomycin

Antimicrobial

MMR-II

MMR

25 mcg

Neomycin

Antimicrobial

Pediarix

DTaP+HepB+IPV

≤ 0.05 ng

Neomycin

Antimicrobial

Pentacel

DTaP+IPV+Hib

< 4 pg

Neomycin

Antimicrobial

ProQuad

MMRV

< 16 mcg

Neomycin

Antimicrobial

Quadracel

DTaP+IPV

< 4 pg

Neomycin

Antimicrobial

RabAvert

Rabies

<1 mcg

Neomycin

Antimicrobial

Vaqta

HepA

<10 ppb (residual)

Neomycin

Antimicrobial

Varivax

Varicella

Trace amounts

Neomycin

Antimicrobial

Zostavax

Varicella Zoster

Trace amounts

Neomycin Sulfate

Antimicrobial

Afluria

Influenza

≤3 ng

Neomycin Sulfate

Antimicrobial

Imovax

Rabies

<150 mcg

Neomycin Sulfate

Antimicrobial

Twinrix

HepA+HepB

≤ 20 ng

Nonylphenol Ethoxylate

Surfactant

Fluvirin

Influenza

≤0.015% w/v

Octoxynol-10 (Triton X-100)

Surfactant

Fluarix Quad

Influenza

≤ 0.115 mg

Octoxynol-10 (Triton X-100)

Surfactant

Flublok

Influenza

≤ 100 mcg

Octylphenol Ethoxylate (Triton X-100)

Surfactant

FluZone

Influenza

≤ 150 mcg/0.5mL

Octylphenol Ethoxylate (Triton X-100)

Surfactant

FluZone High-Dose

Influenza

≤250 mcg

Octylphenol Ethoxylate (Triton X-100)

Surfactant

FluZone Intradermal Quad

Influenza

≤50 mcg

Octylphenol Ethoxylate (Triton X-100)

Surfactant

FluZone Quad

Influenza

≤250 mcg/0.5mL

Peptone

Medium Nutrient

DT

TD

Amount not specified in Package Insert

Peptone, Soy

Medium Nutrient

Comvax

Hib+HepB

Amount not specified in Package Insert

Peptone, Soy

Medium Nutrient

Prevnar

Pneumococcal 7-valent

Growth medium

Peptone, Soy

Medium Nutrient

Prevnar 13

Pneumococcal 13-valent

Growth medium

Peptone, Soy

Medium Nutrient

Recombivax HB

HepB

Ingredient of fermentation medium

Peptone, Soy

Medium Nutrient

Tetanus Toxoid

TT

Ingredient of fermentation medium

Phenol

Preservative, antibacterial

Comvax

Hib+HepB

Ingredient in purification procedure

Phenol

Preservative, antibacterial

PedvaxHIB

Hib+HepB

Ingredient in purification procedure

Phenol

Preservative

Pneumovax 23

Pneumococcal 23-valent

Saline containing 0.25%  phenol

Phenol

Preservative, antibacterial

Typhim Vi

Typhoid

0.25%

Phenol Red Indicator

pH indicator, dye

Imovax

Rabies

20 mcg

Phenol Red Indicator

pH indicator, dye

Rotarix

Rotavirus

Ingredient of Growth Medium

Phosphate Buffer

Buffer

Afluria

Influenza

20 mcg monobasic potassium phosphate

80 mcg monobasic sodium phosphate
300 mcg diabasic sodium phosphate

Phosphate Buffer

Buffer

Cervarix

HPV

0.624 mg sodium dihydrogen phosphate dihydrate

Phosphate Buffer

Buffer

Engerix-B

HepB

0.98 mg/mL disodium phosphate dihydrate
0.71 mg/mL sodium dihydrogen phosphate dihydrate

Phosphate Buffer

Buffer

Flublok

Influenza

0.195 mcg monobasic sodium phosphate

1.3 mg dibasic sodium phosphate

Phosphate Buffer

Buffer

FluMist Quad

Influenza

0.96 mg/0.2 mL d ose monobasic potassium phosphate
2.26 mg/dose dibasic potassium phosphate

Phosphate Buffer

Buffer

FluZone High-Dose

Influenza

Sodium phosphate-buffered isotonic sodium chloride solution - “quantity sufficient to appropriate volume”

Phosphate Buffer

Buffer

FluZone Intradermal Quad

Influenza

Sodium phosphate-buffered isotonic sodium chloride solution - “quantity sufficient to appropriate volume”

Phosphate Buffer

Buffer

FluZone Quad

Influenza

Sodium phosphate-buffered isotonic sodium chloride solution - “quantity sufficient to appropriate volume”

Phosphate Buffer

Buffer

FluZone Quad

Influenza

Sodium phosphate-buffered isotonic sodium chloride solution - “quantity sufficient to appropriate volume”

Phosphate Buffer

Buffer

Ixiaro

Japanese Encephalitis

potassium dihydrogen phosphate

0.5 mL phosphate buffered saline

Phosphate Buffer

Buffer

Menactra

Meningococcal

Amount not specified in Package Insert

Phosphate Buffer

Buffer

MMR-II

MMR

Sodium phosphate, amount not specified

Phosphate Buffer

Buffer

ProQuad

MMRV

36 mcg potassium phosphate dibasic
72 mcg potassium phosphate monobasic
0.34 mg sodium phosphate dibasic

Phosphate Buffer

Buffer

Rotarix

Rotavirus

Sodium phosphate in DMEM (medium)

Phosphate Buffer

Buffer

RotaTeq

Rotavirus

Sodium phosphate monobasic monohydrate

Phosphate Buffer

Buffer

Twinrix

HepA+HepB

Amount not specified in Package Insert

Phosphate Buffer

Buffer

Typhim Vi

Typhoid

0.065 mg disodium phosphate
0.023 mg monosodium phosphate

Phosphate Buffer

Buffer

Varivax

Varicella

0.08 mg potassium phosphate monobasic
0.45 mg sodium phosphate dibasic
Sodium phosphate monobasic, trace amounts

Phosphate Buffer

Buffer

Zostavax

Varicella Zoster

0.10 mg potassium phosphate monobasic
0.57 mg sodium phosphate monobasic

Polymyxin

Antimicrobial

Fluvirin

Influenza

≤3.75 mcg

Polymyxin B

Antimicrobial

Afluria

Influenza

≤ 0.5 ng

Polymyxin B

Antimicrobial

IPOL

Polio

25 ng

Polymyxin B

Antimicrobial

Kinrix

DTaP+IPV

0.01 ng

Polymyxin B

Antimicrobial

Pediarix

DTaP+HepB+IPV

0.01 ng

Polymyxin B

Antimicrobial

Pentacel

DTaP+IPV+Hib

< 4 pg

Polymyxin B sulfate

Antimicrobial

Quadracel

DTaP+IPV

< 4 pg

Polysorbate 20

Surfactant

Flublok

Influenza

≤ 27.5 mcg (Tween 20)

Polysorbate 20

Surfactant

Havrix

HepA

0.05 mg/mL

Polysorbate 20

Surfactant

Twinrix

HepA+HepB

Amount not specified in Package Insert

Polysorbate 80

Surfactant

Boostrix

Tdap

≤ 100 mcg (Tween 80)

Polysorbate 80

Surfactant

Fluad

Influenza

1.175 mg

Polysorbate 80

Surfactant

Fluarix Quad

Influenza

≤ 0.550 mg (Tween 80)

Polysorbate 80

Surfactant

Flucelvax Quad

Influenza

≤1125 mcg (Tween 80)

Polysorbate 80

Surfactant

Flulaval Quad

Influenza

≤887 mcg

Polysorbate 80

Surfactant

Gardasil

HPV

50 mcg

Polysorbate 80

Surfactant

Gardasil 9

HPV

50 mcg

Polysorbate 80

Surfactant

Infanrix

DTaP

≤ 100 mcg (Tween 80)

Polysorbate 80

Surfactant

JE-Vax

Japanese Encephalitis

< 0.0007%

Polysorbate 80

Surfactant

Kinrix

DTaP+IPV

≤ 100 mcg (Tween 80)

Polysorbate 80

Surfactant

Pediarix

DTaP+HepB+IPV

≤ 100 mcg (Tween 80)

Polysorbate 80

Surfactant

Pentacel

DTaP+IPV+Hib

10 ppm

Polysorbate 80

Surfactant

Prevnar 13

Pneumococcal 13-valent

100 mcg

Polysorbate 80

Surfactant

Quadracel

DTaP+IPV

10 ppm

Polysorbate 80

Surfactant

RotaTeq

Rotavirus

Amount not specified in Package Insert

Polysorbate 80

Surfactant

Trumenba

Meningococcal Group B

0.018 mg

Porcine DNA

Residual Medium

Rotarix

Rotavirus

PCV-1

Porcine DNA

Residual Medium

RotaTeq

Rotavirus

PCV-1 and PCV-2

Potassium Aluminum Sulfate

Adjuvant

Comvax

Hib+HepB

Amount not specified in Package Insert

Potassium Aluminum Sulfate

Adjuvant

Recombivax HB

HepB

Amount not specified in Package Insert

Potassium Chloride

Buffer

Afluria

Influenza

20 mcg

Potassium Chloride

Buffer

ProQuad

MMRV

60 mcg

Potassium Chloride

Medium Nutrient

Rotarix

Rotavirus

Ingredient of DMEM medium

Potassium Chloride

Buffer

Varivax

Varicella

0.08 mg

Potassium Chloride

Buffer

Zostavax

Varicella Zoster

0.10 mg

Potassium Glutamate

Stabilizer

RabAvert

Rabies

1 mg

Protamine Sulfate

Protein Purifier

Ixiaro

Japanese Encephalitis

≤ 1 mcg/mL

Salts and Sugars, Inorganic

Medium Nutrient

BioThrax

Anthrax

Amount not specified in Package Insert

Salts, Inorganic

Medium Nutrient

Twinrix

HepA+HepB

Sodium chloride

Salts, Mineral

Adjust tonicity

ActHIB

Hib

0.4% sodium chloride in diluent

Salts, Mineral

Adjust tonicity

Afluria

Influenza

4.1 mg sodium chloride

Salts, Mineral

Adjust tonicity

Bexsero

Meningococcal Group B

3.125 mg sodium chloride

Salts, Mineral

Adjust tonicity

BioThrax

Anthrax

0.85% sodium chloride

Salts, Mineral

Adjust tonicity

Boostrix

Tdap

4.5 mg sodium chloride

Salts, Mineral

Adjust tonicity

Cervarix

HPV

4.4 mg sodium chloride

Salts, Mineral

Adjust tonicity

Comvax

Hib+HepB

0.9% sodium chloride

Salts, Mineral

Adjust tonicity

Engerix-B

HepB

9 mg/mL sodium chloride

Salts, Mineral

Adjust tonicity

Flublok

Influenza

4.4 mg sodium chloride

Salts, Mineral

Adjust tonicity

Gardasil

HPV

9.56 mg sodium chloride

Salts, Mineral

Adjust tonicity

Gardasil 9

HPV

9.56 mg sodium chloride

Salts, Mineral

Adjust tonicity

Hiberix

Hib

0.9% sodium chloride in diluent

Salts, Mineral

Adjust tonicity

Infanrix

DTaP

4.5 mg sodium chloride

Salts, Mineral

Adjust tonicity

Kinrix

DTaP+IPV

4.5 mg sodium chloride

Salts, Mineral

Adjust tonicity

Menhibrix

Meningococcal CY+Hib

0.9% sodium chloride

Salts, Mineral

Adjust tonicity

MMR-II

MMR

Sodium chloride, amount not specified

Salts, Mineral

Adjust tonicity

Pediarix

DTaP+HepB+IPV

4.5 mg sodium chloride

Salts, Mineral

Adjust tonicity

PedvaxHIB

Hib+HepB

0.9% sodium chloride

Salts, Mineral

Adjust tonicity

ProQuad

MMRV

2.4 mg sodium chloride

Salts, Mineral

Adjust tonicity

Recombivax HB

HepB

Ingredient of fermentation medium

Salts, Mineral

Adjust tonicity

Rotarix

Rotavirus

In DMEM (Dulbecco’s Modified Eagle Medium)

Salts, Mineral

Adjust tonicity

Tenivac

Td

Sodium chloride, amount not specified

Salts, Mineral

Adjust tonicity

Twinrix

HepA+HepB

Sodium chloride, amount not specifieds

Salts, Mineral

Adjust tonicity

Typhim Vi

Typhoid

4.150 mg soldium chloride

Salts, Mineral

Adjust tonicity

Vaqta

HepA

0.9% sodium chloride

Salts, Mineral

Adjust tonicity

Varivax

Varicella

3.2 mg sodium chloride

Salts, Mineral

Adjust tonicity

YF-Vax

Yellow Fever

Diluent

Salts, Mineral

Adjust tonicity

Zostavax

Varicella Zoster

3.99 mg sodium chloride

Sodium Bicarbonate

Buffer

ProQuad

MMRV

0.17 mg

Sodium Borate

Buffer

Comvax

Hib+HepB

35 mcg (decahydrate)

Sodium Borate

Buffer

Gardasil

HPV

35 mcg

Sodium Borate

Buffer

Gardasil 9

HPV

35 mcg

Sodium Borate

Stabilizer

Vaqta

HepA

70  mcg

Sodium Citrate

Adjust pH

RotaTeq

Rotavirus

Amount not specified in Package Insert

Sodium Deoxycholate

Surfactant

Fluarix Quad

Influenza

≤ 65 mcg

Sodium Deoxycholate

Surfactant

Flulaval Quad

Influenza

≤ 50 mcg

Sodium Hydroxide

 

RotaTeq

Rotavirus

 

Sodium Metabisulphite

Stabilizer

Ixiaro

Japanese Encephalitis

≤ 200 ppm

Sodium Pyruvate

Medium Nutrient

Rotarix

Rotavirus

in DMEM (medium)

Sodium Taurodeoxycholate

Protein Purifier

Afluria

Influenza

≤ 10 ppm (residual amounts)

Sorbitan Trioleate

 

Fluad

Influenza

1.172 mg

Sorbitol

Stabilizer, solvent

MMR-II

MMR

14.5 mg

Sorbitol

Stabilizer, solvent

ProQuad

MMRV

1.8 mg

Sorbitol

Stabilizer, solvent

Rotarix

Rotavirus

Amount not specified in Package Insert

Sorbitol

Stabilizer, solvent

YF-Vax

Yellow Fever

Amount not specified in Package Insert

Streptomycin

Antimicrobial

IPOL

Polio

200 ng

Succinate Buffer

Stabilizer

Prevnar 13

Pneumococcal 13-valent

295 mcg

Sucrose

Stabilizer

ActHIB

Hib

8.5% 

Sucrose

Stabilizer

Bexsero

Meningococcal Group B

10 mg

Sucrose

Stabilizer

FluMist Quad

Influenza

13.68 mg/dose

Sucrose

Stabilizer

JE-Vax

Japanese Encephalitis

40% w/v

Sucrose

Stabilizer

Menhibrix

Meningococcal CY+Hib

12.6 mg

Sucrose

Stabilizer

MMR-II

MMR

1.9 mg

Sucrose

Stabilizer

Pentacel

DTaP+IPV+Hib

42.5 mg

Sucrose

Stabilizer

ProQuad

MMRV

≤ 21 mg

Sucrose

Stabilizer

Rotarix

Rotavirus

Amount not specified in Package Insert

Sucrose

Stabilizer

RotaTeq

Rotavirus

Amount not specified in Package Insert

Sucrose

Stabilizer

Varivax

Varicella

25 mg

Sucrose

Stabilizer

Vivotif

Typhoid

26-130 mg/capsule

Sucrose

Stabilizer

Zostavax

Varicella Zoster

31.16 mg

Thimerosal

Preservative

Afluria

Influenza

24.5 mcg mercury

Thimerosal

Manufacturing Residual

DT

DT

≤ 0.3 mcg mercury, trace amounts

Thimerosal

Preservative

Flulaval Quad

Influenza

< 25 mcg mercury

Thimerosal

Preservative

Fluvirin

Influenza

25 mcg mercury/dose in multi-dose vial; ≤ 1 mcg/dose mercury in prefilled syringe

Thimerosal

Preservative

Fluzone

Influenza

25 mcg mercury/0.5mL

Thimerosal

Preservative

Fluzone Quad

Influenza

25 mcg mercury in multi-dose vial

Thimerosal

Preservative

JE-Vax

Japanese Encephalitis

0.007%

Thimerosal

Preservative

Menomune

Meningococcal

25 mcg mercury/dose in multi-dose diluent

None in single-dose

Thimerosal

Manufacturing Residue

Td

Td

≤ 0.3 mcg mercury, trace amounts

Vero Cells

Growth Medium

IPOL

Polio

Amount not specified in Package Insert

Vero cells

Medium Nutrient

Ixiaro

Japanese Encephalitis

Amount not specified in Package Insert

Vero Cells

Growth Medium

Kinrix

DTaP+IPV

Amount not specified in Package Insert

Vero Cells

Growth Medium

Pediarix

DTaP+HepB+IPV

Amount not specified in Package Insert

Vero Cells

Growth Medium

Rotarix

Rotavirus

Amount not specified in Package Insert

Vero Cells

Growth Medium

RotaTeq

Rotavirus

Amount not specified in Package Insert

Vitamins

Medium Nutrient

BioThrax

Anthrax

Ingredient of growth medium

Vitamins

Medium Nutrient

Cervarix

HPV

Ingredient of growth medium

Vitamins

Protein Purifier

Fluarix Quad

Influenza

≤ 0.135 mg α-tocopheryl hydrogen succinate

Vitamins

Protein Purifier

Flublok

Influenza

Ingredient of growth medium

Vitamins

Protein Purifier

Flulaval Quad

Influenza

≤ 320 mcg α-tocopheryl hydrogen succinate

Vitamins

Medium Nutrient

Gardasil

HPV

Ingredient of growth medium

Vitamins

Medium Nutrient

Gardasil 9

HPV

Ingredient of growth medium

Vitamins

Medium Nutrient

MMR-II

MMR

Ingredient in grown media

Vitamins

Medium Nutrient

Rotarix

Rotavirus

Amount not specified in Package Insert

Xanthan

Thickening agent

Rotarix

Rotavirus

Ingredient  in diluent

Yeast

Medium Nutrient

Comvax

Hib+HepB

≤ 1% yeast protein

Yeast

Medium Nutrient

Engerix-B

HepB

≤ 5% yeast protein

Yeast

Medium Nutrient

Gardasil

HPV

< 7 mcg yeast protein/dose

Yeast

Medium Nutrient

Gardasil 9

HPV

< 7 mcg yeast protein/dose

Yeast

Medium Nutrient

Menveo

Meningococcal

Ingredient in growth medium

Yeast

Medium Nutrient

Pediarix

DTaP+HepB+IPV

≤ 5% yeast protein

Yeast

Medium Nutrient

Prevnar

Pneumococcal 7-valent

Ingredient of growth medium

Yeast

Medium Nutrient

Prevnar 13

Pneumococcal 13-valent

Ingredient of growth medium

Yeast

Medium Nutrient

Recombivax HB

HepB

< 1% yeast protein

Yeast

Medium Nutrient

Twinrix

HepA+HepB

≤ 5% yeast protein

Yeast

Medium Nutrient

Vivotif

Typhoid

Amount not specified in Package Insert

 

This information is correct to the best of our knowledge.  Any inaccuracies should be reported to us at info@hopkinsvaccine.org

This table was last updated on September 22, 2016

© 2016 Institute for Vaccine Safety