Components of

DTaP Vaccines

Components Page
Excipients Table
Allergens Table
       
Name Daptacel Infanrix
Manufacturer sanofi pasteur GlaxoSmithKline
Viability Inactivated bacterial vaccine Inactivated bacterial vaccine
Indicated Ages 6 wks-7 yrs 6 wks-7 yrs
Dose 0.5 mL 0.5 mL
Schedule 5 dose series: 2,4,6 and 15-20 mos, 4-6 yrs 5 dose series: 2,4,6 and 15-20 mos, 4-6 yrs
Route Intramuscular Intramuscular
Appearance White cloudy suspension after shaking Turbid white suspension after shaking
Concentration Diphtheria, 15 Lf
Tetanus, 5 Lf
Pertussis, 10mcg
Filamentous hemagglutinin, 5 mcg
Pertactin, 3mcg
Fimbriae types 2 and 3, 5 mcg
Diphtheria, 25 Lf
Tetanus, 10 Lf
Pertussis, 25 mcg
Filamentous hemagglutinin, 25 mcg
Pertactin, 8 mcg
Preservative 2-Phenoxyethanol, 3.3 mg (0.6% v/v) None
Adjuvant Aluminum Phosphate, 0.33 mg Aluminum Hydroxide, 0.625 mg
Excipients 2-Phenoxyethanol, 3.3 mg (0.6% v/v)
Formaldehyde, ≤5 mcg
Glutaraldehyde, 50 ng
Formaldehyde, ≤100 mcg
Polysorbate 80, ≤100 mcg
Sodium chloride, 4.5 mg/mL
Allergens None The tip caps of the prefilled syringes contain natural rubber latex
Media Bordetella pertussis
Stainer-Scholte medium
Modified by Casamino Acids and Dimethyl-beta-cyclodextrin

Corynebacterium diphtheria
Modified Mueller’s growth medium
Purified using Ammonium Sulfate Fractionation
Detoxified using Formalin

Clostridium tetani
Mueller-Miller Casamino acid medium
Detoxified using formalin
Purified by Ammonium Sulfate fractionation
Bordetella pertussis
Modified Stainer-Scholte liquid medium

Corynebacterium diphtheria
Fenton medium containing bovine extract
Detoxified using Formaldehyde
PT detoxified using Glutaraldehyde
FHA and Pertactin detoxified using formaldehyde

Clostridium tetani
Modified Lantham medium derived from bovine casein
Detoxified using formaldehyde
Packaging 0.5 mL vials 0.5 mL vials and disposable prefilled syringes
Storage 2-8°C (35-46°F)
Do not freeze
2-8°C (35-46°F)
Do not freeze
PI date Oct 2013 Oct 2016
    table last updated 10/6/17